PDRN REGENERATIVE Microneedling
Experience advanced skin rejuvenation with PDRN Rejuvenation Microneedling — a treatment combining the collagen-stimulating benefits of microneedling with regenerative PDRN to support skin repair, hydration and renewal.
Designed to improve overall skin quality, this treatment helps target fine lines, uneven texture, dullness and dehydration, leaving the skin looking smoother, healthier and more radiant.
SKIN QUALITY OVER VOLUME
What Are PDRN'S?
PDRN stands for Polydeoxyribonucleotide. PDRNs are purified fragments of DNA that are used in regenerative skin treatments to support the skin’s natural repair and renewal processes.
They work by helping to create an environment that supports cellular repair, fibroblast activity and tissue regeneration. Fibroblasts are the cells responsible for producing important components of healthy skin, including collagen and elastin.
PDRN also has anti-inflammatory and tissue-repairing properties, making it particularly beneficial for skin that is dull, dehydrated, ageing or in need of recovery.
When combined with microneedling, the controlled micro-channels created during treatment allow the PDRN serum to be applied effectively while microneedling simultaneously stimulates the skin’s own healing response.
The result is a treatment focused not only on improving the appearance of the skin, but on supporting healthier, stronger and more resilient skin from within.
PDRN'S are suitable for a wide range of skin concerns, including:
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Fine lines and crepey skin
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Loss of firmness and elasticity
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Dehydrated or dull-looking skin
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Thin, fragile or ageing skin
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Under-eye skin concerns
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Acne scarring and post-inflammatory skin damage
They are particularly effective for skin that feels tired, compromised or lacking vitality.
Treatment Areas
PDRN Rejuvenation Microneedling can be used to improve skin quality across a number of areas, including:
• Face – for overall rejuvenation, texture, fine lines and radiance
• Neck – to target crepey skin, fine lines and loss of elasticity
• Décolletage – to improve texture, hydration and visible signs of ageing
• Hands – to rejuvenate thin, ageing or sun-damaged skin
• Areas of scarring – to support skin remodelling and improve the appearance of certain scars
How Does the Treatment Work?
PDRN Rejuvenation combines microneedling with a regenerative PDRN serum to support skin repair and renewal.
Microneedling creates thousands of controlled micro-channels within the skin, triggering the body’s natural healing response and stimulating the production of collagen and elastin.
During the treatment, PDRN is applied to the skin, allowing the serum to work alongside the microneedling process. PDRN consists of purified DNA fragments that support cellular repair and regeneration, helping to improve overall skin quality.
Together, these processes help to improve hydration, texture, firmness and radiance, while softening the appearance of fine lines and supporting healthier, more resilient-looking skin.
What to Expect (The Client Journey)
Your treatment will begin with a consultation to discuss your skin concerns and ensure PDRN Rejuvenation Microneedling is suitable for you.
The skin is thoroughly cleansed and prepared before a microneedling device is passed over the treatment area. PDRN serum is applied throughout the treatment, allowing it to work alongside the controlled micro-channels created by microneedling.
Following treatment, your skin may appear red, warm or slightly sensitive, similar to mild sunburn. You may also experience some dryness or mild flaking as the skin renews. This is temporary and typically settles over the following few days.
Results develop gradually as the skin’s natural repair and renewal processes take place, with the complexion becoming smoother, more hydrated, radiant and refreshed.
Results & Treatment Plan
Following PDRN Rejuvenation Microneedling, skin can begin to look fresher, smoother and more hydrated, with further improvements developing gradually as the skin’s natural renewal processes continue.
For optimal results, a course of 3 treatments spaced approximately 4–6 weeks apart is recommended. This allows each treatment to build upon the last, supporting ongoing collagen production, skin repair and improvements in overall skin quality.
Depending on your individual skin concerns, maintenance treatments can then be carried out throughout the year to help maintain your results.
Results vary from person to person and your recommended treatment plan will be tailored to your skin during consultation.
Who Is This Treatment For?
PDRN Rejuvenation Microneedling is ideal for anyone looking to improve their overall skin quality while supporting the skin’s natural repair and renewal processes.
It may be particularly suited to those concerned with:
• Fine lines and early signs of ageing
• Dull, tired or lacklustre skin
• Dehydration and loss of radiance
• Uneven skin texture
• Loss of firmness and elasticity
• Enlarged pores
• Mild acne scarring
• Skin that feels in need of repair or rejuvenation
This treatment is a great choice for clients wanting more than traditional microneedling, with the added regenerative benefits of PDRN to support healthier, smoother and more radiant-looking skin.
Suitability will always be assessed during consultation and treatment will be tailored to your individual skin concerns and goals.
Frequently Asked Questions
What is PDRN?
PDRN stands for Polydeoxyribonucleotide. It consists of purified DNA fragments used in regenerative skin treatments to support the skin’s natural repair and renewal processes. When combined with microneedling, it provides an advanced treatment focused on improving hydration, texture and overall skin quality.
Is PDRN really made from salmon DNA?
PDRN used in many regenerative skin treatments is derived from highly purified DNA fragments obtained from salmon-family fish. This is why you may have heard PDRN treatments referred to as a “salmon DNA facial.”
The DNA undergoes a purification process before being formulated for use within aesthetic skin treatments. If you have a known fish or salmon allergy, please let me know before treatment so the product ingredients and your suitability can be assessed.
What product do you use?
For my PDRN Rejuvenation Microneedling treatment, I use Kiera Reju. It is applied during the microneedling procedure to complement the skin’s natural repair and renewal response.
Does the treatment hurt?
The treatment is generally well tolerated. You may experience some mild discomfort or sensitivity as the microneedling device passes over the skin, particularly around more delicate areas.
How much downtime is there?
Downtime is usually minimal. Your skin may look red and feel warm, tight or slightly sensitive immediately afterwards, similar to mild sunburn. Mild dryness or flaking can also occur over the following few days.
When will I see results?
You may notice your skin looking fresher and more hydrated following treatment. Improvements in texture, radiance and overall skin quality develop gradually as the skin’s natural repair and renewal processes continue.
How many treatments will I need?
For optimal results, I recommend a course of 3 treatments approximately 4–6 weeks apart. Maintenance treatments can then be carried out throughout the year depending on your individual skin concerns and goals.
What's the difference between PDRN Rejuvenation and basic microneedling?
Basic microneedling stimulates the skin’s natural healing response and encourages collagen and elastin production. PDRN Rejuvenation combines microneedling with Kiera Reju, providing an advanced option for clients wanting additional support for hydration, repair, rejuvenation and overall skin quality.
Can I wear makeup afterwards?
I recommend avoiding makeup for at least 24 hours following your treatment to allow the skin time to recover.
What should I avoid after treatment?
For the first 24–48 hours, avoid strenuous exercise, swimming, saunas, steam rooms and excessive heat. Strong active skincare ingredients should also be avoided while the skin recovers. Daily SPF is particularly important following microneedling.
Can anyone have PDRN Rejuvenation Microneedling?
Not everyone will be suitable for treatment. A consultation will be carried out beforehand to discuss your medical history, medications, allergies and skin concerns. Treatment may need to be postponed or avoided in certain circumstances, including active skin infections or irritation, pregnancy or breastfeeding.
Do I need to prepare my skin before treatment?
You may be advised to temporarily stop retinoids, exfoliating acids and other potentially irritating active skincare before your appointment. Full pre-treatment and aftercare guidance will be provided.
Can I combine PDRN Rejuvenation with other treatments?
Yes. Depending on your skin concerns, PDRN Rejuvenation Microneedling can form part of a wider personalised skin plan. Where other treatments are being performed, appropriate treatment intervals will be recommended.
Prices
1
Single Treatment
£160 per session
✔ Skin repair & regeneration
✔ Improves elasticity & texture
✔ Strengthens overall skin quality
✔ No added volume
2
Course of 2
£300
(Save £20)
✔ Ideal for first-time clients
✔ Gentle introduction to regenerative skin treatments
3
Course of 3
£430
(Save £50)
✔ Recommended for visible skin repair
✔ Supports collagen and long-term skin quality
✔ Most popular option
“PDRN REGENERATIVE microneedling is £160 per session.
Because skin repair happens gradually, most clients see the best results with a course, which is why I offer savings when treatments are paid for together.”